Galantamine supplement information - Health benefit and side effects of galantamine
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Galantamine information
Galantamine supplement
MInd Power Rx -- brain
boosting formula
Galantamine is a cholinergic medicine. Galantamine
can be isolated from several plants, including daffodil bulbs, but is now synthesized. Galantamine is available over the counter and also by prescription.
Galantamine offsets reductions in central
cholinergic neurotransmission in Alzheimer's disease by specifically and reversibly
inhibiting the acetylcholinesterase enzyme. This allows more acetylcholine to be available in
the brain. Galantamine is also a nicotinic receptor agonist. Another herbal
extract that has potential in the therapy of Alzheimer's disease is Huperzine A.
Being approved for the treatment of Alzheimer's
disease in both the US and in Europe, galantamine has potential
as therapy for dementia. Galantamine is currently not recommended for use
by young individuals.
Galantamine
side effects
Side effects of galantamine are similar to those of
other cholinesterase inhibitors. High doses may lead to side effects such as nausea, vomiting, diarrhea, abdominal pain, and
dyspepsia.
GalantaMind
is a formulation featuring galantamine, a
phytonutrient extracted from the common snowdrop (Galanthus nivalis), daffodil
(Narcissus pseudonarcissus L.), and spider lily (Lycoris radiata), among other
plants.
As an acetylcholinesterase inhibitor, galantamine competitively blocks the premature, age-related breakdown of the natural neurotransmitter acetylcholine, an essential molecule that supports memory function. Unlike other acetylcholinesterase inhibitors, galantamine also enhances nicotinic receptor activity, an effect long known to influence memory and intellectual activity.
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GalantaMind also contains the nutrients choline and vitamin B5, the precursor and cofactor, respectively, to the body's production of acetylcholine.
NOTE: Please consult with your physician before you purchase galantamine to make sure this product is appropriate for you. Galantamine is also sold as Reminyl, a prescription medicine.
Suggested Use: For adults only. Half or one
galantamine capsule in the
morning a few times a week with breakfast
* Galantamine daily value not established
Mind Power Rx - Formulated by Ray
Sahelian, M.D.
Mind Power Rx is a sophisticated cognitive formula. It combines a delicate
balance of brain circulation agents and neurotransmitter precursors with
powerful natural brain chemicals that support:
• Memory and Mood
• Mental clarity
• Concentration
• Alertness & Focus
Why buy all the individual herbs and nutrients separately -- at great
expense -- when you can buy this excellent combination?
The herbs in Mind Power Rx include:
Ashwagandha, Bacopa, Fo-Ti,
Ginkgo biloba, Ginseng, Gotu kola, Mucuna pruriens, Reishi, and Rhodiola. The nutrients and
vitamins in Mind Power Rx include Acetyl-l-carnitine, Carnitine,
Carnosine,
Choline, DMAE, Inositol, Methylcobalamin, Pantothenic acid, Trimethylglycine,
Tyrosine, and Vinpocetine.
Galantamine for Alzheimer's disease
Economic and clinical benefits of galantamine in the treatment of mild to
moderate Alzheimer's disease in a Korean population: a 52-week prospective
study.
J Korean Med Sci. 2008 February. Department of Psychiatry, Hallym University
College of Medicine, Seoul, Korea.
To evaluate the impact of galantamine treatment on the function, caregiver time,
and resource used in the treatment of patients with mild to moderate Alzheimer's
disease, costs and outcomes were evaluated during a 52-week prospective,
randomized, double-blind, community-controlled trial of galantamine. Patients
received either galantamine treatment (n=72) or no treatment (n=66). The
analysis was performed from a societal perspective. Galantamine treatment
reduced time spent caring for the patients and maintained improved functional
capacity, whereas, when no treatments were given, a great increase in caregiver
time and progressive functional deteriorations were observed. Galantamine had a
beneficial effect not only to slow functional decline in patients with mild to
moderate AD, but also to save a substantial amount of costs, closely related to
reduction in caregiver burden and decrease in caregiver time.
Galantamine for Nerve Gas Exposure
Treatment with galantamine in combination with atropine, protects guinea
pigs from lethal doses of the nerve agents sarin and soman and the insecticide
parathion. The toxic effect of these "organophosphorus" compounds derives from
irreversible blockage of an enzyme critical to nerve function. The end result
can be seizures and cardiac arrest. At present, atropine and other drugs are
used to treat the toxic effects of organophosphorus compounds. However, these
treatments have various limitations, including an inability to fully protect the
brain from damage. Galantamine protects nerves from these chemicals by
temporarily blocking the same enzyme. Researchers tested the effects of
galantamine in guinea pigs exposed to lethal doses of sarin, soman, and paraoxon,
the biologically active form of parathion. Atropine was given to counter the
effects of these agents outside the brain. Galantamine plus atropine safely and
effectively counteracted the toxic effects of the organophosphorus compounds.
Moreover, galantamine was well tolerated at the dosages needed to prevent death.
Proceeding of the National Academy of Sciences, August 2006.
Galantamine Research Update
Indicators of neuroprotection with galantamine.
Brain Res Bull. 2005 Jan 30;64(6):519-24. Geerts H.
In Silico Biosciences, 686 Westwind Drive, Berwyn, PA
Alzheimer's disease is pathologically characterized by neurofibrillary
tangles and beta-amyloid plaques. These observations form the basis for a large
number of disease-modifying therapeutic approaches, which might ultimately lead
to neuroprotection and enhanced survival of neurons. Recent data suggest a role
for cholinergic stimulation, especially the alpha7 nicotinic acetylcholine
receptors (nAChR), in beta-amyloid-mediated neurotoxicity. As galantamine is a
modest acetylcholinesterase inhibitor in addition to being an allosteric
modulator of nicotinic acetylcholine receptors, it is interesting to study the
clinical effects of this compound in the light of its neurochemical properties
to discern potential neuroprotective effects. The review presents the
preclinical evidence in Alzheimer-related models of neuroprotection with
galantamine, especially in models related to glutamate and beta-amyloid toxicity
in vitro and to cholinergic stress in vivo. There is substantial evidence that
these effects occur by upregulation of the protective protein bcl-2 and are
mediated via alpha7 nicotinic acetylcholine receptors. The review also
identifies possible clinical indicators, such as long-term studies, suggesting a
neuroprotective effect for galantamine mediated by alpha7 nicotinic receptors.
These clinically relevant neuroprotective properties of galantamine are
worthwhile exploring further and their clinical relevance may improve the
development of new disease-modifying agents.
Galantamine supplement emails
Q. What are the differences between galantamine supplement and the physician
prescribed Reminyl prescription drug?
A. This is a good question. As far as we know, they are identical,
but we really have not seen the exact chemical analysis of Reminyl drug to know for sure.
Q. I wish to take
galantamine for memory I not worried about it and the stoke. My main concern was
about the safety of galantamine after hearing something about Reminyl for
Alzheimer's and 16 people dieing in trials. can you give you input?
A. I don't have enough personal and professional
experience with galantamine to make any recommendations. We suggest having
approval by your doctor. I prefer other mind nutrients and consider galantamine
as a supplement to be used only when the others are not effective.
Q. It galantamine the same generic
version of Razadyne?
A. As far as we know, the Razadyne generic name is galantamine.
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